Chris O'Brien Lifehouse Research Institute | Chris O'Brien Lifehouse

Chris O’Brien Lifehouse

Research Institute

Welcome to the Chris O’Brien Lifehouse Research Institute 

Since opening as a not-for-profit comprehensive cancer centre in 2013, Chris O’Brien Lifehouse has developed a diverse research program across all cancer types. Our research spans translational research, clinical trials, clinical outcomes, and health services research. The establishment of the Chris O’Brien Lifehouse Research Institute in 2025 underscores our commitment to advancing clinical practice and care through patient-centred research.

Our impact extends beyond institutional boundaries, driving innovation through collaborations with local and international partners. Patients are at the heart of everything we do. By engaging with consumers, we ensure our research tackles the issues most relevant to our patients, paving the way for meaningful translation of findings into clinical practice.

The Chris O’Brien Lifehouse Research Institute represents the next phase in our mission to improve outcomes for people affected by cancer.

Hear from Professor Lisa Horvath, Chief Clinical Officer and Director of Research, on the evolution of the Chris O’Brien Lifehouse Research Institute.

Research Spotlight

Our research spotlight highlights some of our key research hubs and streams that are pushing boundaries to deliver innovative, cutting-edge treatments for our patients. Click through to explore our latest advancements.

Arto Hardy Family Biomedical Innovation Hub

Arto Hardy Family Biomedical Innovation Hub

Head and Neck

Head and Neck

Gynae-oncology

Gynae-oncology

Neuro-oncology

Neuro-oncology

Sarcoma

Phase I Clinical Trials

Phase I Clinical Trials

We’re searching for ground-breaking discoveries. To do that, we need three key pillars.

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Clinical Trials

We’re one of the largest cancer clinical trials centres in Australia, giving more patients access to latest treatments.

Researchers

Our clinicians, researchers and scientists are one in the same, meaning patient care is underpinned by discovery.

Collaboration

Game-changing research needs a generous philanthropic community and global collaborative network.

Research-driven care in FY24

Publications associated with changes in clinical practice locally, nationally and internationally
10% yearly increase in publication
Total number of COBL publications of clinical intervention studies
COBL international collaboration on publications

20 publications

223 publications

45 publications

78 publications

COBL publications in top 10% citation percentiles
Total field weighted citation impacts or equivalent
Increase investigator-initiated clinical trials (10% year-on-year)
Total peer review funding commencing FY24

48 publications

2.37

14 trials ongoing

$10M

Estimated
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